The Helen J. Serini Foundation's mission focuses on supporting innovative interventions that tackle the root causes of systemic barriers to health, safety, shelter, and opportunity in the communities it serves. It aims for a world where every individual, regardless of means or identity, is treated equitably and has the opportunity to thrive. The foundation envisions its role not just in funding but also in increasing its impact through convening and connecting nonprofit partners, investing in capacity building and leadership development, influencing policy and advocacy for system change, and leveraging resources to foster greater change.