The National Institutes of Health (NIH), a part of the U.S. Department of Health and Human Services, is the nation’s medical research agency — making important discoveries that improve health and save lives.
The focus of this grant program is on the clinical validation of candidate biomarkers for neurological diseases and conditions. It aims to support the rigorous validation of biomarker measurements within the clinical population of interest. This entails establishing the biomarker's positive and negative predictive values in line with FDA guidelines. The grant assumes the biomarker has been identified, detection technology developed and analytically validated, and the research or clinical need and potential context of use has been determined.